Nuclear Magnetic Resonance (NMR) is first and foremost an analytical technique allowing detection, identification and quantification of chemical or biological samples.Using more sophisticated methods, NMR can also be used to determine molecular structures, in particular those of biological macromolecules, proteins, nucleic acids etc. In structural biology, NMR is used as an alternative to the other major technique, X-ray crystallography, because (i) some proteins refuse to crystallize and (ii) NMR samples are analysed in aqueous solution, thus allowing studies of the and interactions of biological samples closer to their native conditions in the cell.

In 2011, a consortium consisting of laboratories from the IBPC, the Pasteur Institute and the Université Paris Descartes obtained funding in the form of the EquipEx CACSICE, that allowed the installation of large equipment in the three institutes. A Brucker 700 MHz NMR solid/liquid spectrometer was installed at the IBPC in 2014 and equipped with a cryo-probe thanks to joint funding from DYNAMO, CACSICE and SESAME in 2018.



Contact :

Scientist in charge :

Pierre Barraud


Platform engineer :

Christel Le Bon

(IR CNRS - UMR7099)

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